?glioblastoma

glioblastoma發(fā)音

英：[?gl???bl?'st??m?]　　美：[?gl?o?bl?'sto?m?]

英：　　美：

glioblastoma中文意思翻譯

n. 膠質(zhì)母細(xì)胞瘤 惡性膠質(zhì)瘤；成膠質(zhì)細(xì)胞瘤

glioblastoma常見例句

1 、Objective This study aims to screen the differentially expressed genes of glioblastoma using microarray technology.───目的用生物芯片篩選膠質(zhì)母細(xì)胞瘤相關(guān)基因。

2 、Clinical study on progrostic scale for patients with glioblastoma multiforme───多形性膠質(zhì)母細(xì)胞瘤預(yù)后分級研究

3 、Glioblastoma multiform (GBM) is the most common type of primary brain tumor according for more than 40% of neoplasm in the central nervous system.───神經(jīng)膠質(zhì)瘤是主要的原發(fā)性腦部腫瘤，占到了中樞神經(jīng)系統(tǒng)腫瘤的40%。

4 、It's called a glioblastoma it's one of the fastest moving brain cancers.─── 那是惡性膠質(zhì)瘤 是轉(zhuǎn)移最快的腦腫瘤之一

5 、Glioblastoma (GBM) only rarely occurs congenitally and has not been fully characterized.───很少有先天性的惡性膠質(zhì)瘤（GBM），它還沒有被充分地研究。

6 、Objective Tor improve the recognization of some special morphological types of glioblastoma.───目的提高對膠質(zhì)母細(xì)胞瘤的某些特殊形態(tài)類型的認(rèn)識。

7 、Objective: To explore MRI features of peritumoral infarction following resection of glioblastoma multiforme (GBM) and evaluate their clinical significance.───摘要目的：探討膠質(zhì)母細(xì)胞瘤術(shù)后瘤周梗塞的MRI特征，并評價其臨床意義。

8 、I would carefully review the MRI and vigorously rule out glioblastoma first.───我會查看患者M(jìn)RI情況，首先排除膠質(zhì)母細(xì)胞瘤。

9 、Objective To evaluate the main treatment methods and safety for long-time survival patients of glioblastoma.───目的探討腦惡性膠質(zhì)瘤長期生存患者的主要治療方法和安全性。

10 、Only 3 percent of people with glioblastoma surie fie years, with the aerage surial being just under a year.───只有百分之三患了膠質(zhì)母細(xì)胞瘤的病人能存活五年以上，平均存活期只有不到一年。

11 、An allelotype study of primary and corresponding recurrent glioblastoma multiforme───復(fù)發(fā)前后多形性膠質(zhì)母細(xì)胞瘤的等位基因譜分析

12 、MRI images often show a ring-enhancing lesion surrounded by edema, a picture indistinguishable from glioblastoma, abscess, and other tumors (including metastasis).───MRI圖像顯示一環(huán)形水腫**損，常難以與惡性膠質(zhì)瘤、潰瘍以及其它腫瘤（包括轉(zhuǎn)移灶）相鑒別。

13 、Proliferation and radiosensitivity in human primary culture glioblastoma multiforme───原代培養(yǎng)多形性膠質(zhì)母細(xì)胞瘤的增殖與放射敏感性

14 、Expression absence of LRRC4 gene in glioblastoma cell lines───LRRC4基因在腦膠質(zhì)瘤細(xì)胞系中表達(dá)缺失

15 、We review recent data that stem cells of glioblastoma, a highly malignant brain tumour, seem to be dependent on cues from aberrant vascular niches that mimic the normal neural stem cell niche.───我們回顧了惡性膠質(zhì)瘤干細(xì)胞的最新數(shù)據(jù)，其似乎依賴于模仿正常神經(jīng)干細(xì)胞微環(huán)境的異常所提供的線索。這些數(shù)據(jù)對該腫瘤有著直接的意義。

16 、Giant cell glioblastoma───巨細(xì)胞成神經(jīng)膠質(zhì)細(xì)胞瘤

17 、Aim:To study the dynamic expression of green fluorescent protein (GFP) and enhanced green fluorescent protein (EGFP) on C6 glioblastoma cells in vivo.───目的:研究綠色熒光蛋白報道基因體外轉(zhuǎn)染C6膠質(zhì)瘤細(xì)胞系的動態(tài)表達(dá)。

18 、The influences of VM-26 on proliferation in human glioblastoma multiforme BT-325───VM-26對人多形性膠質(zhì)母細(xì)胞瘤BT-325細(xì)胞增殖的影響

19 、Previous research had analyzed the protein and lipid content of glioblastoma microvesicles.───前期的研究分析了腦腫瘤微泡的蛋白質(zhì)成分和脂肪成分。

20 、Establishment of a human glioblastoma multiforme cell line "BT_(325)───人腦多形性膠質(zhì)母細(xì)胞瘤細(xì)胞系“BT325”的建立及其生物學(xué)特性

21 、They then began an experiment on 21 patients who had been diagnosed with glioblastoma.───接著，他們開始在21名此前被診斷患有成膠質(zhì)細(xì)胞瘤的病人身上進(jìn)行一項實驗。

22 、His team studied 20 different batches of glioblastoma cells in the lab and found that many growth switches were flipped on at once.───他的團(tuán)隊研究了實驗室里的20批不同的膠質(zhì)母細(xì)胞瘤細(xì)胞，發(fā)現(xiàn)很多生長調(diào)控點瞬間會變化。

23 、Leading the list were reports on pancreatic cancer and glioblastoma, the deadliest cancers.───排在成果首位的是胰腺癌和膠質(zhì)母細(xì)胞瘤、兩種最致命的癌癥。

24 、Apoptosis of glioblastoma multiforme cells induced by VM-26 treatment in vitro───VM-26誘導(dǎo)膠質(zhì)母細(xì)胞凋亡的實驗研究

25 、It appears as if the treatment you were receiving in the clinical trial has slowed the growth of the glioblastoma.─── 看來你在臨床試驗中 接受的治療 減緩了惡性膠質(zhì)瘤的增長

26 、He designed it so that you'd manifest the symptoms of a glioblastoma.─── 他設(shè)計的藥物 讓你產(chǎn)生 惡性膠質(zhì)瘤的癥狀

27 、Both are symptoms of glioblastoma, a highly aggressive brain tumor.─── 兩者都是惡性膠質(zhì)瘤的癥狀 是種致死率極高的腦部腫瘤

28 、Methods:VEGF antisense eDNA was transfected into C6 glioblastoma cells mediated with Lipofectamine. The inhibitory of VEGF antisense RNA on the proliferation and apoptosis of C6 cells in vitro were obserced.───方法用Lipofectamine介導(dǎo)的方法將VEGF反義eDNA轉(zhuǎn)染入C6鼠膠質(zhì)瘤細(xì)胞系,觀察其對細(xì)胞增殖和凋亡的影響。

29 、primary glioblastoma───原發(fā)膠質(zhì)母細(xì)胞瘤

30 、Stratmann A, Risau W, Plate K H. Cell typespecific expression of angiopoietin1 and angiopoietin2 suggests a role in Glioblastoma angiogenesis. Am J Pathol,1998,14591466.───王鈞,吳開春,張德新等.人血管生成素1基因轉(zhuǎn)染對胃癌細(xì)胞體內(nèi)致瘤力及血管生成的影響.中華腫瘤雜志,2005,27:7780.

31 、They discovered cytomegalovirus in the tumours of more than 90% of those people with glioblastoma whom they examined, but not in healthy brain tissue, nor in non-m alignant brain tumours.───他們在所檢查過的90%以上患成膠質(zhì)細(xì)胞瘤的病人的腫瘤內(nèi)發(fā)現(xiàn)了巨細(xì)胞病毒，而在健康的腦組織和良性腦瘤中均沒發(fā)現(xiàn)。

32 、Kill Effect of Herpes Simplex Virus Thymidine Kinase Gene on Human Multiform Glioblastoma Cells───單純皰疹病毒胸苷激酶基因?qū)θ四z質(zhì)母細(xì)胞瘤細(xì)胞的殺傷效應(yīng)研究

33 、Keywords loss of heterozygosity（LOH） glioblastoma tumor suppressor genes;───關(guān)鍵詞雜合性缺失;膠質(zhì)母細(xì)胞瘤;腫瘤抑制基因;

34 、Wrann M，Thomas L，Larry K，et al.T cell suppressor factor from human glioblastoma cells is a 12.5 kd protein related to transforming growth factor.The EMBO Joural，1987，6：1633.───林彤，浦佩玉，鐘述猷。神經(jīng)膠質(zhì)瘤患者細(xì)胞免疫功能變化及其降低機(jī)制.中國免疫學(xué)雜志，1991，4：238.

35 、Glioblastoma multiform is one of the most common types of primary central nervous system tumors with dismal prognosis.───摘要多形性腦膠質(zhì)母細(xì)胞瘤是最常見的顱內(nèi)腫瘤之一且預(yù)后差。

36 、glioblastoma multiforme───多形性成膠質(zhì)細(xì)胞瘤

37 、Andropov he he designed it so that you'd manifest the symptoms of a glioblastoma.─── 安德羅波夫...他... 他設(shè)計的藥物 讓你產(chǎn)生 惡性膠質(zhì)瘤的癥狀

38 、The normal prognosis for glioblastoma is death within two years, even if a patient is treated with chemotherapy and radiation.───對成膠質(zhì)細(xì)胞瘤，一般預(yù)測病人在兩年內(nèi)死亡，即使他接受化療和放療。

39 、Expression and Significance of Urokinase - type Plasminogen Activator in Glioblastoma───尿激酶型纖溶酶原激活劑在膠質(zhì)母細(xì)胞瘤中表達(dá)及意義

40 、Invasion is a defining hallmark of glioblastoma multiforme, just as metastasis characterizes other high-grade tumors.───侵襲是多形性惡性膠質(zhì)瘤的特征之一，就如同轉(zhuǎn)移是低分化腫瘤的特征一樣。

41 、Keywords Glioblastoma;Phage li-brary;Tumor targeting;Whole cell screening;───關(guān)鍵詞神經(jīng)膠質(zhì)細(xì)胞瘤;噬菌體肽庫;腫瘤導(dǎo)向;全細(xì)胞篩選;

42 、Glioblastoma Multiform───多行性腦膠質(zhì)母細(xì)胞瘤

43 、Objective To explore the clinical significance and the expression of phosphorylated c-Jun N-terminal kinase (p-JNK) and phosphorylated c-Jun (p-c-Jun) in glioblastoma (GBM).───目的探討**酸化JNK(p-JNK)與**酸化c-Jun(p-c-Jun)在多形性膠質(zhì)母細(xì)胞瘤(GBM)中的表達(dá)及意義。

44 、Multiform peripheral blood lymphocyte gene expression spectrum in glioblastoma patients───惡性膠質(zhì)瘤患者外周血淋巴細(xì)胞基因表達(dá)譜的研究

45 、An allelotype study of human glioblastoma───人膠質(zhì)母細(xì)胞瘤等位基因譜分析的研究

46 、Results This case is consistent with the criteria on the glioblastoma mutiforme following cerebral trauma in literatures.───結(jié)果本病例完全符合文獻(xiàn)中關(guān)于腦外傷后膠質(zhì)瘤的判定標(biāo)準(zhǔn)。

47 、Nursing care of postoperative polymorph glioblastoma patients undergoing combined chemotherapy───多形性膠質(zhì)母細(xì)胞瘤術(shù)后聯(lián)合化療病人的護(hù)理

48 、The research suggests it could be very effective in cases of glioblastoma.─── 研究稱這是 治療膠質(zhì)母細(xì)胞瘤很有效的辦法

49 、Glioblastoma with sarcomatous component───神經(jīng)膠質(zhì)母細(xì)胞瘤伴肉瘤成分

50 、STUDY OF WHOLE-MOUNT CYTOSKELETON OF HUMAN GLIOBLASTOMA BT_(325) CELLS BY CARBONPLATINUM COATING AND IMMUNOELECTRON MICROSCOPY───用碳-鉑復(fù)型與免疫電鏡技術(shù)對人腦膠質(zhì)瘤細(xì)胞系BT_(325)整裝細(xì)胞骨架的研究

51 、Nomograms based on long follow-up data from chemoradiotherapy in glioblastoma multiforme can now help to predict the prognosis of the individual patient.───基于多形性膠質(zhì)母細(xì)胞瘤化放療后的長期隨訪資料的數(shù)據(jù)圖，現(xiàn)在可以用于預(yù)測不同患者的預(yù)后。

52 、Study on allelic imbalance of chromosome 7 in primary glioblastoma multiforme───原發(fā)性多形性膠質(zhì)母細(xì)胞瘤7號染色體等位基因失平衡狀況的研究

53 、METHODS and MATERIAL: The study population includes 22 patients with recurrent glioblastoma who underwent Thallium-201 Single Photon Emission Computerized Tomography (Tl 201 SPECT)and Magnetic Resonance Imaging (MRI).───方法：22例復(fù)發(fā)的膠質(zhì)母細(xì)胞瘤經(jīng)歷了鉈201單光子發(fā)射計算機(jī)斷層掃描（Tl201SPECT）和核磁共振成像（MRI）檢查。

54 、Keywords piezoelectric sensor;nucleic acid aptamer;self-assembly;glioblastoma cell;───壓電傳感器;核酸適體;自組裝;星形膠質(zhì)瘤細(xì)胞;

55 、Human glioblastoma cells(HGC),human embryonic pulmonary cells(HEPC),monkey kidney cells(V-116)and K562 cells were infected by T. gondii. The infective states were observed by electron microscope.───用電鏡觀察了弓形蟲在人腦惡性膠質(zhì)瘤細(xì)胞（HGC）、人胚肺細(xì)胞（HEPC）、人K562細(xì)胞和猴腎細(xì)胞（V－116）中感染和寄生狀況及受感染細(xì)胞的病理變化。

56 、14. Randomized Phase II Trial of Chemoradiotherapy Followed by Either Dose-Dense or Metronomic Temozolomide for Newly Diagnosed Glioblastoma.───對初步診斷為膠質(zhì)母細(xì)胞瘤采用劑量密集型或節(jié)拍型替莫唑胺給藥的隨機(jī)II期臨床化放療實驗。

57 、3. CONCLUSION: SEGA is a benign,slowly growing and possible multidifferentiated tumor,and it should be differentiated from giant cell glioblastoma,gemistocytic astrocytoma and ependymoma.───結(jié)論:SEGA為生長緩慢的良性腫瘤,生存時間長,預(yù)后良好,可能具有多向分化潛能,病理確診須與巨細(xì)胞性膠質(zhì)母細(xì)胞瘤、肥胖細(xì)胞性星形細(xì)胞瘤和室管膜瘤等鑒別。收藏指正

58 、This glioblastoma multiforme (GBM) demonstrates marked cellularity with marked hyperchromatism and pleomorphism.───多形性膠質(zhì)母細(xì)胞瘤(GBM)顯示腫瘤細(xì)胞深染和多形性。

59 、Keywords loss of heterozygosity;allelotype;glioblastoma;tumor suppressor genes;───雜合性丟失;等位基因譜分析;膠質(zhì)母細(xì)胞瘤;腫瘤抑制基因;

60 、Objective:To find out the effective method of establishing rat C6 glioblastoma model ,and assess the feasibility of dynamic observasion with MRI.───目的:探索建立大鼠C6膠質(zhì)瘤模型的有效方法,了解MRI動態(tài)檢測腫瘤的可行性。

61 、A final analysis was carried out for the 81 patients with glioblastoma (median age, 73 years;───最終分析了膠質(zhì)母細(xì)胞瘤81例(年齡70歲--85歲、平均73歲)。

62 、Human glioblastoma───人腦星型膠質(zhì)母細(xì)胞瘤

63 、one example is temozolomide, which is the only chemotherapy available for treating brain tumours such as glioblastoma multiforme and progressive anaplastic astrocytoma.───一個例子是替莫唑胺，這是目前唯一用于治療腦腫瘤，如多形性惡性膠質(zhì)瘤和進(jìn)展性多形性成膠質(zhì)細(xì)胞瘤的化療藥物。

64 、It accounts for 40%-45% of all human primary brain tumors.Because of high vascularity, glioblastoma multiforme can be used as an ideal model for angiogenesis and anti-angiogenesis study.───由于其特異性的高度血管化,多型性膠質(zhì)母細(xì)胞瘤可作為研究腫瘤血管化生成過程和抗血管化治療的理想模型。

65 、Glioblastoma muhiforme───多形性膠質(zhì)母細(xì)胞瘤

66 、Background There is no community standard for the treatment of glioblastoma in patients 70 years of age or older.───背景：對于70歲以上（含70歲）的老年惡性膠質(zhì)瘤患者的治療尚無公認(rèn)的標(biāo)準(zhǔn)。

67 、The other two studies are looking at the effect of measles on recurrent oarian cancer and a type of brain tumor called glioblastoma multiforme.───另兩項試驗用于測試麻疹病毒治療復(fù)發(fā)卵巢癌和一種腦腫瘤多形性膠質(zhì)母細(xì)胞瘤。

68 、multiform glioblastoma───多形性成膠質(zhì)細(xì)胞瘤, 多形性惡性膠質(zhì)瘤

69 、“MGMT silencing is currently being used as a prognostic indicator of successful alkylation chemotherapy for glioblastoma;───他們寫到：“目前使用MGMT沉默現(xiàn)象來作為預(yù)測烷基化化療治療膠質(zhì)母細(xì)胞瘤預(yù)后效果的指標(biāo)；

70 、Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer.───多形性膠質(zhì)母細(xì)胞瘤(GBM)是最常見的致命性的腦部腫瘤。

71 、The endogenous regulation of self-renewal in human glioblastoma stem cells───人膠質(zhì)瘤干細(xì)胞內(nèi)在自我更新能力

72 、Next, the scientists deliered slow-release BMP4-containing "beads" directly into mouse brains with implanted glioblastoma cells.───其次，給小鼠植入膠質(zhì)瘤細(xì)胞后，科學(xué)家再將一種可以緩慢釋放BMP4的珠狀物直接注入小鼠腦細(xì)胞中。

73 、Every patient is different, of course, and you should know we have no data on this application with a glioblastoma like yours.─── 當(dāng)然 每個病人都不一樣 你要知道 對于像你這樣的膠質(zhì)母細(xì)胞瘤 我們沒有這方面的應(yīng)用數(shù)據(jù)

74 、In the past few years the government has spent $100 million dollars for genome studies in lung and ovarian cancers and glioblastoma multiforme, a type of brain tumor.───在過去的幾年中，政府為肺癌、卵巢癌、腦膠質(zhì)母細(xì)胞瘤（一種腦組織腫瘤）的基因組研究上投入了1億美元。

75 、MRI and ultrasound technique have improved the diagnosis of glioblastoma and increased clinical value for themselves.───摘要MRI與超聲技術(shù)在膠質(zhì)細(xì)胞瘤的診斷中不斷改進(jìn)，增強了臨床診斷價值。

76 、Mechanisms of drug effect and recurrence of glioblastoma should be put in more emphasis for research work.───有待加強對藥物作用機(jī)制、腫瘤復(fù)發(fā)機(jī)制方面的研究。

77 、recurring glioblastoma───復(fù)發(fā)腦膠質(zhì)母細(xì)胞瘤

78 、The prognosis for patients with glioblastoma multiforme (GBM), the most common primary brain tumor, is dismal.───多形性膠質(zhì)母細(xì)胞瘤(GBM)是常見的原發(fā)性腦腫瘤，患者的預(yù)后不佳。

79 、Methods A case of glioblastoma contained foci epithelial differentiation (adenoid glioblastoma) was analyzed with HE and immunohistochemical stains and review of the literature.───方法采用HE染色、免疫組化對1例術(shù)后病理證實為腺樣膠質(zhì)母細(xì)胞瘤的病例進(jìn)行詳細(xì)的觀察。

80 、Keywords loss of heterozygosity;glioblastoma;genes;suppress or;tumor;───雜合性丟失;膠質(zhì)母細(xì)胞瘤;基因;抑制;腫瘤;

81 、Most middle-aged, anaplastic astrocytoma showed the peak incidence at 50 years of age, while the glioblastoma multiforme tumor incidence peaks about 10 years later.───中年人最多，間變性星形膠質(zhì)細(xì)胞瘤發(fā)病在50歲呈高峰，而多形性膠質(zhì)母細(xì)胞瘤發(fā)病高峰晚10年左右。

82 、It will make her glioblastoma respond better to her clinical trial.─── 這會讓她的膠質(zhì)母細(xì)胞瘤 對臨床試驗起更好的反應(yīng)

83 、Glioblastoma multiforme (GBM) is the most common glioma (a type of brain cancer).───最常見的膠質(zhì)瘤，大約占原發(fā)性腦腫瘤的1/4。

84 、SEGA is a benign,slowly growing and possible multidifferentiated tumor,and it should be differentiated from giant cell glioblastoma,gemistocytic astrocytoma and ependymoma.───SEGA為生長緩慢的良性腫瘤,生存時間長,預(yù)后良好,可能具有多向分化潛能,病理確診須與巨細(xì)胞性膠質(zhì)母細(xì)胞瘤、肥胖細(xì)胞性星形細(xì)胞瘤和室管膜瘤等鑒別。

85 、Conclusion Postoperative radiotherapy plus concomitant adjuvant chemotherapy for glioblastoma seems to be beneficial with minimal additional toxicity.───結(jié)論術(shù)后同步放化療對腦惡性膠質(zhì)瘤患者具有潛在的治療價值,并很少增加毒性反應(yīng)。

86 、In addition, the drug resulted in a significant, 27% increase of survival of mice with glioblastoma tumours and a shrinking of glioblastoma tumours in rats.───此外，該藥物使惡性膠質(zhì)瘤小鼠的生存率增加了27 %，使大鼠惡性膠質(zhì)瘤體積縮小。

87 、If this is a primary brain tumor, possibilities include medulloblastoma (rare, but does occur in older individuals) and small cell variant of glioblastoma.───如果這是原發(fā)于腦的腫瘤，可能的診斷是髓母細(xì)胞瘤（罕見，但確實可以在老年人中出現(xiàn)）和膠質(zhì)母細(xì)胞瘤的小細(xì)胞變異型。

88 、Grade IV gliomas (glioblastoma multiforme).Surgery is required to establish tissue diagnosis and debulk the lesion.───WHO四級膠質(zhì)瘤（多形性膠質(zhì)母細(xì)胞瘤）：同樣需要手術(shù)來達(dá)到組織病理診斷和減小腫瘤體積。

抗瘧疾藥物本芴醇是如何抑制膠質(zhì)母細(xì)胞瘤的？

作為一種相當(dāng)致命的腦癌，膠質(zhì)母細(xì)胞瘤（glioblastoma）患者的五年生存率一直非常低（不到 6%）。

好消息是，弗吉尼亞聯(lián)邦大學(xué)的科學(xué)家們，剛剛為傳統(tǒng)抗瘧疾藥物找到了新的應(yīng)用場景。

結(jié)合有限的放療和替莫唑胺（Temoside）化療，小鼠實驗已表明了抗瘧疾藥物的有效性。

Paul B. Fisher，來自：Virginia Commonwealth University

通常情況下，膠質(zhì)母細(xì)胞瘤會表現(xiàn)出對這些標(biāo)準(zhǔn)護(hù)理方式的抗性，導(dǎo)致惡性腫瘤繼續(xù)在大腦中**。

不過新研究發(fā)現(xiàn)，本芴醇效果取決于被稱作 Fli-1 的遺傳因子在應(yīng)對膠質(zhì)母細(xì)胞瘤治療抗性的新認(rèn)知。

其能夠調(diào)節(jié)膠質(zhì)母細(xì)胞瘤中 aa 突體蛋白的表達(dá)（即“熱休克蛋白”HSPB1），為干預(yù)和限制惡性腫瘤的生長開辟了新的可能。

弗吉尼亞聯(lián)邦大學(xué)團(tuán)隊借助先進(jìn)的篩選技術(shù)來尋找可抑制 Fli-1 的藥物，結(jié)果發(fā)現(xiàn)當(dāng)前已獲批準(zhǔn)的抗瘧疾藥物本芴醇（lumefantrine）具有這種獨特的能力。

據(jù)悉，本芴醇可以與 Fli-1 結(jié)合并使之失活，從而終止驅(qū)動腫瘤形成的基因的表達(dá)。有鑒于此，研究團(tuán)隊決定通過一些實驗測試來證明。

在早期體外研究中，膠質(zhì)母細(xì)胞瘤細(xì)胞會在放療和化療的情況下繼續(xù)生長。但在摻入本芴醇之后，便可有效殺死癌細(xì)胞并抑制腫瘤的生長。

在第二輪小鼠研究中，研究團(tuán)隊再次發(fā)現(xiàn)它能夠抑制腫瘤細(xì)胞的生長，即便是那些曾經(jīng)對放化療表現(xiàn)出抗性的癌細(xì)胞。

除了靶向 HSPB1，該團(tuán)隊的工作還表明，該藥物對另外兩種機(jī)制也產(chǎn)生了影響 —— 細(xì)胞外基質(zhì)（ECM）重塑和上皮間質(zhì)的轉(zhuǎn)化，也受 Fli-1 的調(diào)節(jié)和被該藥物抑制。

首席研究員 Paul B. Fisher 表示，這些臨床前研究為膠質(zhì)母細(xì)胞瘤的 Fli-1 / HSPB1 抑制提供了堅實的依據(jù)，有助于推動治療腦癌等疾病的新方法。

有關(guān)這項研究的詳情，已經(jīng)發(fā)表在近日出版的《美國國家科學(xué)院院刊》（PNAS）上。

原標(biāo)題為《Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma》。

什么是細(xì)胞瘤

病情分析：細(xì)胞瘤也就是造釉細(xì)胞瘤是一種比較常見的、來自牙源性上皮的頜骨中心性腫瘤。瘤細(xì)胞的形態(tài)與牙胚中的造釉細(xì)胞相似，故稱為造釉細(xì)胞瘤。發(fā)病人群造釉細(xì)胞瘤多見于青壯年。 細(xì)胞瘤也就是造釉細(xì)胞瘤是一種比較常見的、來自牙源性上皮的頜骨中心性腫瘤。瘤細(xì)胞的形態(tài)與牙胚中的造釉細(xì)胞相似，故稱為造釉細(xì)胞瘤。發(fā)病人群造釉細(xì)胞瘤多見于青壯年。 腎母細(xì)胞瘤，它屬于是一種胚胎性的惡性一個腫瘤，多半認(rèn)為源于腎胚基細(xì)胞。腎母細(xì)胞瘤好發(fā)于兒童，是兒童第二位常見的腹部惡性腫瘤，98%的病例發(fā)生于10歲以下，最多見于3歲以下的兒童。