cirrhosis是什么意思,cirrhosis中文翻譯,cirrhosis發(fā)音、用法及例句
?cirrhosis
cirrhosis發(fā)音
英:[s??r??s?s] 美:[s??ros?s]
英: 美:
cirrhosis中文意思翻譯
硬化, 肝硬化
cirrhosis詞形變化
形容詞: cirrhotic |
cirrhosis常見例句
1 、LR for HCC in cirrhosis should be performed with caution;there were no long-term survivors in our data.───對肝硬化的肝癌患者應(yīng)該慎重采用LR手術(shù),目前我們還沒有這些患者長期存活的數(shù)據(jù)。
2 、Serum lipids were measured in the patients with hepatoma, liver cirrhosis and controls.───我們對肝細(xì)胞瘤、肝硬化以及對照人員作了血脂測定。
3 、Following the liver cirrhosis degree progress,the abnormal rate of AST/ALT ratio tended to ascend(?P?───(2 )不同級別肝硬化患者AST/ALT比值異常率之間的線性趨勢有顯著性意義 (P
4 、Ten of 12 liver cirrhosis tissues were positive with a positive rate of 83.3%. 5 of 6 NRH were positive with a positive rate of 83.3%.───22例癌旁組織中有14例**,**率為63.6%;12例肝硬變組織中有10例**,**率為83.3%;
5 、Metcalf JV,Mitchison HC.Natural history of early primary biliary cirrhosis[J].Lancet,1996,348(9039):1399.───張巖,白雪帆.原發(fā)性膽汁性肝硬化的研究進(jìn)展[J].陜西醫(yī)學(xué)雜志,2005,34(7):833.
6 、Patients cycled between the following health states: viral suppression, ongoing viremia, seroconversion, hepatocellular carcinoma, cirrhosis and death.───**患者經(jīng)歷以下的疾病狀態(tài):病毒抑制、病毒血癥期、血清轉(zhuǎn)化、肝細(xì)胞癌、肝硬化和死亡。
7 、Objective To understand the variation of serum lipid and apoprotein in posthepatitic cirrhosis and biliary cirrhosis.───摘要目的探討病毒性肝炎肝硬化與膽汁性肝硬化之間的血脂、載脂蛋白變化及其臨床意義。
8 、For patients at the late period of cirrhosis, it effectively increases the plasma protein and holds in seroperitoneum.───對于肝硬化后期的人,能有效地提高血漿蛋白,控制腹腔積水。
9 、The typical patient has obvious signs of advanced nutritional cirrhosis.───典型的病人有明顯的晚期營養(yǎng)性肝硬變的體癥。
10 、Cirrhosis deaths, in both males and females increased during the same years.───在這些年里,不論男女,因肝硬化而死亡的人數(shù)也同時(shí)增加。
11 、You regret it at the end, and then you come back with cirrhosis of the liver and a trail of broken relationships.─── 最后你們都會后悔 拖著患有肝硬化的身體 與支離破碎的家庭關(guān)系而來
12 、However, OKT4+ cells tended to increase when eAg-positive CAH converted into eAb-positive or/and progressed to cirrhosis.───在HBeAb**的CAH和肝硬化患者中,OKT_8~+**細(xì)胞雖未減少,但OKT_4~+細(xì)胞相對增多。
13 、Objective The aim of this study was to describe the interdigestive gastroduodenal motility in patients with decompensated cirrhosis.───摘要目的研究肝硬化失代償期患者空腹胃腸動力有無異常。
14 、Serum LPO and red blood celI SOD,of 106 patients with virus hepatitis andposthepatitis cirrhosis were tested.───對106例病毒性肝炎、肝炎后肝硬化患者進(jìn)行血漿過氧化脂質(zhì)(LPO)和紅細(xì)胞超氧化物歧化酶(SOD)的檢測。
15 、Generally, chylothorax secondary to liver cirrhosis is hard to manage and the prognosis is poor.───一般而言,肝硬化并發(fā)乳糜胸通常是難以處理且預(yù)后不佳。
16 、In any event, its seriousness must not be discounted because of the possibilities of complications in later life, such as cirrhosis of the liver.───在任何情況下,都不能忽視這種肝炎的嚴(yán)重性,因?yàn)橐院笥锌赡馨l(fā)生肝硬化這樣的并發(fā)癥。
17 、Globally, 57% of cirrhosis was attributable to either Hepatitis B or Hepatitis C.───全球,57%的肝硬化是**或丙肝造成。
18 、Micronodular cirrhosis is seen along with moderate fatty change.───伴中度脂肪變性的小結(jié)節(jié)型肝硬化。
19 、MMP_(1) gene expression maintained at relative high level in reversal of liver cirrhosis.───在肝硬化的自發(fā)逆轉(zhuǎn)過程中MMP_(1)基因表達(dá)保持在明顯高于正常對照的水平。
20 、To osteomyelitis, diabetes, liver cirrhosis, cancer have the good curative effect.───對骨髓炎、糖尿病、肝硬化、癌癥均有較好療效。
21 、Oh, we don't recommend bud for cirrhosis.─── 我們不建議肝硬化的人吸大麻
22 、We present a 66-year-old patient who has been a victim of HBV related liver cirrhosis and polycystic kidney disease for years.───在此,我們報(bào)告一例66歲B型肝炎并肝硬化,多發(fā)性腎囊腫的婦人,因上腹脹痛經(jīng)超音波影像檢查發(fā)現(xiàn)一個(gè)左肝多囊性肝腫瘤。
23 、There was no significant difference in different Child-Pugh class of cirrhosis.───不同肝功能分級的肝硬化患者間血清瘦素水平差異不顯著。
24 、Moreover, but may also use in diabetes, liver cirrhosis, cancer and osteomyelitis's treatment.───另外,還可用于糖尿病、肝硬化、癌癥及骨髓炎的治療。
25 、A team at London's Hammersmith Hospital is attempting to reverse cirrhosis of the liver by harnessing and enhancing the body's own repair mechanism.───倫敦哈默史密斯醫(yī)院的一個(gè)小組嘗試以控制并提高身體自己的修補(bǔ)機(jī)制,來反轉(zhuǎn)肝的硬化。
26 、Here is another example of macronodular cirrhosis.───另例大結(jié)節(jié)型肝硬化。
27 、There are also some patients with liver cirrhosis showed a number of complications, such as melena, hematemesis.───也有部分患者表現(xiàn)為肝硬化的一些并發(fā)癥,如黑便、嘔血。
28 、He's a salty old drunk with cirrhosis, but the point is, you got to hold on to what matters in life.─── 他是個(gè)有肝硬化的酒鬼 但重點(diǎn)是 你得抓住人生中真正重要的東西
29 、Liver cirrhosis was induced by oral administration of thioacetamide (TAA) solution(35mg/dl) for experimental group.───以硫代**胺(thioacetamide,TAA)誘導(dǎo)大鼠肝纖維化/肝硬化模型作為實(shí)驗(yàn)組。
30 、Following the liver cirrhosis of different degree progress,the abnormal rate of TBA,TSB,ALB,Ca 2+ tended to ascend(?P?───不同級別肝硬化患者 ,TBA、TSB、ALB、Ca2 +的異常率之間的線性趨勢均有顯著性意義 (P
31 、Although rare, deaths have occurred due to liver failure or blood infection, mostly in persons with cirrhosis.───盡管發(fā)生的概率很低,但由于肝功能喪失和血液感染,死亡也會發(fā)生,大多數(shù)死亡的患者已有肝硬化。
32 、Cirrhosis and pituitary hypogonadism were common in males with this genotype, and one man had cardiomyopathy.───具有這種基因型的男性,肝硬化和腦垂體促性腺功能低下皆很常見,其中一位患有心肌病。
33 、This greater sensitivity to alcohol leaves women more prone to alcohol-related illnesses like cirrhosis of the liver and alcohol-induced brain damage.───對酒精更為敏感,使得女性更容易罹患像肝硬化等與酒精有關(guān)的疾病以及因酒精造成的腦部損害。
34 、We present a case of iliopsoas abscess with a history of Child's class C liver cirrhosis.───我們提出一腰大肌膿瘍,經(jīng)手術(shù)治療成功出院之案例。
35 、If it is initial cirrhosis, like initial F4 then it is a logical diagnosis.───如果是初期肝硬化,例如初期F4,那么它確實(shí)是合理的診斷方法。
36 、It can cause liver cell damage, leading to cirrhosis and cancer.───它可能會破壞肝細(xì)胞,導(dǎo)致肝硬化和肝癌。
37 、You say you have a case of cirrhosis?───你說你有一個(gè)肝硬化的病人,是嗎?
38 、Severe fibrosis or cirrhosis developed in 23 cases, especially in cases with biliary abnormalities in the periphery of the liver.───23例患者發(fā)生肝纖維化或肝硬化,在肝周圍膽管異?;颊咧斜憩F(xiàn)突出。
39 、On 24 Feb 2006, TM was diagnosed to have jaundice. On 27 Feb 2006, he wasadmitted to the hospital for cirrhosis (hardening of liver).───2006年2月24日,TM被診斷得了黃疸。2月27日,因肝硬化送進(jìn)醫(yī)院。
40 、Well, what your results suggest is that you do have cirrhosis.─── 你的檢測結(jié)果顯示 你患有肝硬化
41 、The number of deaths caused by chronic liver disease and cirrhosis for males aged 45 to 64 years is 93.───45至64歲男性因慢性肝病和肝硬變引致的死亡人數(shù)是93。
42 、In TCM, Cirrhosis belongs to hypochondriac pain, accumulation, distension of abdomen and jaundice.───摘要肝硬化在中醫(yī)屬于脅痛、積聚、臌脹、黃疸等范疇。
43 、Chronic infections with Hepatitis B and Hepatitis C virus are well-recognized risk factors for cirrhosis and liver cancer.───慢性**和丙肝病毒感染已經(jīng)被認(rèn)知是造成肝硬化和肝癌的重要危險(xiǎn)系數(shù)。
44 、We know very little as yet about the mental effects of severe cirrhosis of the liver.───對于產(chǎn)生肝硬化的精神作用,我們知之甚少。
45 、HBV has 7 genotypes A to G and it has been postulated that some may have a higher incidence of cirrhosis or and Liver cancer.───**病毒基因型和其變異型是不同的.變異型是在某一個(gè)核苷酸的新變故,而基因型則是一組不同的核苷酸.
46 、Globally, these hepatotropic viruses are the most important causes of cirrhosis and liver cancer.───全球范圍內(nèi),**和丙肝病毒感染是肝硬化和肝癌發(fā)生的最重要的原因。
47 、Micronodular cirrhosis may also be seen with Wilson's disease, primary biliary cirrhosis, and hemochromatosis.───小結(jié)節(jié)型肝硬化也可見于Wilson病、原發(fā)性膽汁硬化和血色素沉著癥。
48 、The number of deaths caused by chronic liver disease and cirrhosis for both sexes with unknown age is 1.───年不詳?shù)哪行约芭砸蚵愿尾『透斡沧円碌乃劳鋈藬?shù)是1。
49 、The number of deaths caused by chronic liver disease and cirrhosis for males with unknown age is 1.───年不詳?shù)哪行砸蚵愿尾『透斡沧円碌乃劳鋈藬?shù)是1。
50 、Our data show that OLT is the option of choice in symptomatic PFIC and whenever liver cirrhosis is present.───我們的數(shù)據(jù)提示無論肝臟纖維化與否,OLT是有癥狀的PFIC的選擇之一。
51 、Well, at least they caught the cirrhosis while there's still something they can do about it.─── 至少在還有得救時(shí) 診斷出這是肝硬化
52 、Two patients with HBeAg-negative hepatitis and 1 with cirrhosis had experienced drug abuse.───2位在成年后肝硬化的組織學(xué)特征消失。
53 、probably cirrhosis from all the booze you fed him.─── 死因應(yīng)該是你們給他灌的酒導(dǎo)致的肝硬化
54 、Prof Pinzani: I could argue with the statement that liver biopsy is the best test for liver cirrhosis.───我可能要對肝活檢是肝硬化的最佳檢驗(yàn)方法提出質(zhì)疑。
55 、The number of deaths caused by chronic liver disease and cirrhosis for both sexes aged 1 to 4 years is 0.───1至4歲男性及女性因慢性肝病和肝硬變引致的死亡人數(shù)是0。
56 、The amount of SCF and the amount and activity of MMP-9 have an important effect on HOC during formation and reduction of rat cirrhosis.───干細(xì)胞因子(SCF)表達(dá)量與MMP-9蛋白及其活性表達(dá)對DMN大鼠肝硬化形成與消減過程中HOC數(shù)量的動態(tài)變化具有重要作用。
57 、Key word : Hepatitis. Cirrhosis(of the liver).chronic hepatitis. Acute hepatitis.───關(guān)鍵詞:肝炎、肝硬化、慢性肝炎、猛暴性肝炎。
58 、This may eventually lead to a macronodular cirrhosis.───它最終可導(dǎo)致大結(jié)節(jié)性肝硬化。
59 、Why " is strong liver soft firm soup " can you treat liver cirrhosis?───為什么“強(qiáng)肝軟堅(jiān)湯”能治療肝硬化?
60 、Abstract: Objective To study correlative valuation of the degree of hepatic cirrhosis and indocyanine green.───摘要 目的 研究肝硬化程度與吲哚氰綠排泄試驗(yàn)的相關(guān)性。
61 、A blast from our queerest past is about to return to our fair capital for some cirrhosis inducing mayhem next week.───org大明王朝歸來下周我們的首都將迎來一場久違的同志大風(fēng)浪。
62 、Jim he's a regular, alcoholic, cirrhosis, seizures.─── 吉姆 ??? 酗酒 肝硬化 癲癇
63 、Hepatology Digest: This next question in on primary biliary cirrhosis.───國際肝?。合乱粋€(gè)問題是關(guān)于原發(fā)性膽汁性肝硬化的。
64 、Dr Tsutomu Nishida and colleagues evaluated whether oral glucose tolerance test was useful in evaluating the prognosis of liver cirrhosis.───Tsutomu Nishida醫(yī)生和同事評估口服葡萄糖耐量測驗(yàn)是否可用于評估肝硬化的惡化.
65 、You have cirrhosis the result of chronic progressive liver disease.─── 你有肝硬化 是長期病變的結(jié)果
66 、About patient of ascites of cirrhosis of the liver total caloric is calculated.───關(guān)于肝硬變腹水患者總熱量的計(jì)算。
67 、It and liver cirrhosis have again different.───它和肝硬化又有不同。
68 、AIM: To improve the diagnosis of early primary biliary cirrhosis (PBC).───摘要目的:提高早期原發(fā)性膽汁性肝硬化的診斷水平。
69 、It has a higher incidence in postnecrotic cirrhosis and hemochromatosis than in Laennec's cirrhosis .───壞死后肝硬變及血色素沉著癥引起的肝癌比門脈性肝硬變所引起者為多。
70 、P: Doctor, I have got cirrhosis, haven't I ?───醫(yī)生,握手肝硬化嗎?
71 、Micronodular cirrhosis is seen along with moderate fatty change. Note the regenerative nodule surrounded by fibrous connective tissue extending between portal regions.───伴中度脂肪變性的小結(jié)節(jié)型肝硬化。注意再生的肝細(xì)胞小結(jié)節(jié)被匯管區(qū)之間的纖維結(jié)締組織包圍。
72 、Prof.Trauner: I think the standard treatment is ursodeoxycholic acid especially for primary biliary cirrhosis.───我認(rèn)為標(biāo)準(zhǔn)治療藥物是熊去氧膽酸,特別是對于原發(fā)性膽汁性肝硬化。
73 、We present a66- year-old patient who has been a victim of HBV related liver cirrhosis and polycystic kidney disease for years.───在此,我們報(bào)告一例66歲B型肝炎并肝硬化,多發(fā)性腎囊腫的婦人,因上腹脹痛經(jīng)超音波圖象檢查發(fā)現(xiàn)一個(gè)左肝多囊性肝腫瘤。
74 、Abstract: Objective To study the efficacy of prostaglandin E1(PEG1)for antifibrosis on active hepatic cirrhosis.───摘 要: 目的觀察前列腺素E1對活動性肝炎肝硬化的抗纖維化療效。
75 、Seventeen (77.3%) patients were associated with liver cirrhosis, nineteen(86.4%)patients had positive AFP by counter- immunoelectrophoretic method.───17例(77.3%)合并有肝硬變,19例(86.4%)的甲胎蛋白對流法為**。
76 、I can't believe I'm still here and not halfway to cirrhosis in a pub.─── 真不敢相信我還在這里 而不是在去酒吧喝到肝硬化的路上
77 、Clinical impression was cryptogenic cirrhosis.───臨床診斷為不明原因的肝硬化。
78 、Thus,the LVI was significantly lower([9.1+0.6]cm/s vs [19.1+1.9]cm/s,P───LVI顯著降低,9.1+0.6vs19.1+1.9(P
79 、Objective To investigate the upper gastrointestinal hemorrhage patients with cirrhosis of health education needs.───摘要目的探討肝硬化上消化道出血患者健康教育需求。
80 、Cirrhosis just means there's scar tissue in her liver.─── 硬化只是說明她的肝臟上有傷疤組織
81 、What distinction do chronic hepatitis and liver cirrhosis have?───慢性肝炎與肝硬化有什么區(qū)別?
82 、Regionally, these infections usually accounted for more than 50% of hepatocellular carcinoma and cirrhosis cases.───地區(qū)性的,這些感染通常占據(jù)50%以上的肝細(xì)胞癌和肝硬化病例。
83 、Micronodular cirrhosis from chronic alcoholism is more common in the U.S. than macronodular cirrhosis following hepatitis B or C infection.───在美國,慢性酒精中毒引起的小結(jié)節(jié)型肝硬化比乙型或丙型肝炎引起的小結(jié)節(jié)型肝硬化更常見。
84 、Gynecomastia may occur with cirrhosis of liver, Leydig cell tumors of testis, or with drugs.───您也可以在線咨詢、在線掛號預(yù)約,診療更便捷、無需排隊(duì)等候。
85 、Chronic hepatitis C irus (HC) has emerged as a leading cause of cirrhosis in the USA and throughout the world.───在美國和世界范圍內(nèi),慢性丙型肝炎病毒作為一個(gè)主導(dǎo)的肝硬化的原因出現(xiàn)。
86 、Other cancers and certain noncancerous conditions, including cirrhosis and hepatitis, may also increase AFP levels.───其他的癌癥和非癌狀態(tài)下,包括肝硬化和肝炎,AFP水平也可能升高。
87 、Infection with hepatitis C virus (HCV) can cause chronic hepatitis, cirrhosis, and even hepatocellular carcinoma (HCC).───摘要丙型肝炎病毒的感染會引起慢性肝炎、肝硬化、甚至肝癌。
88 、Regionally, these infections usually accounted for more than50% of hepatocellular carcinoma and cirrhosis cases.───地區(qū)性的,這些感染通常占據(jù)50%上的肝細(xì)胞癌和肝硬化病例。
89 、Choice of the Hepatic Vascular Occlusion for Resection of Large Liver Cancer with Cirrhosis.───合并肝硬化的大肝癌切除時(shí)肝血供阻斷的選擇。
90 、Here is another example of micronodular cirrhosis.───另例小結(jié)節(jié)型肝硬化。
什么是肝腸化
肝硬化?
肝硬化是臨床常見的慢性進(jìn)行性肝病,由一種或多種病因長期或反復(fù)作用形成的彌漫性肝損害。在我國大多數(shù)為肝炎后肝硬化,少部分為酒精性肝硬化和血吸蟲性肝硬化。病理組織學(xué)上有廣泛的肝細(xì)胞壞死、殘存肝細(xì)胞結(jié)節(jié)性再生、結(jié)締組織增生與纖維隔形成,導(dǎo)致肝小葉結(jié)構(gòu)破壞和假小葉形成,肝臟逐漸變形、變硬而發(fā)展為肝硬化。早期由于肝臟代償功能較強(qiáng)可無明顯癥狀,后期則以肝功能損害和門脈高壓為主要表現(xiàn),并有多系統(tǒng)受累,晚期常出現(xiàn)上消化道出血、肝性腦病、繼發(fā)感染、脾功能亢進(jìn)、腹水、癌變等并發(fā)癥。
英文名稱
liver cirrhosis
淺析:NASH和NAFLD的代謝組學(xué)研究
非酒精性脂肪性肝病(Nonalcoholic fatty liver disease (NAFLD))是一種脂肪在肝臟中積聚的疾病,影響全球約25%的成年人口,是世界上最常見的慢性肝病。NAFLD包括一系列疾病,從最簡單的脂肪變性到非酒精性脂肪性肝炎(Nonalcoholic steatohepatitis (NASH))、肝硬化(cirrhosis)到最嚴(yán)重的肝細(xì)胞癌(Hepatocellular carcinoma)。隨著疾病的進(jìn)展,肝臟脂質(zhì)積聚伴隨著過度的炎癥和氧化應(yīng)激,最終可以檢測纖維化(臨床主要的風(fēng)險(xiǎn)預(yù)測因子)并用于NASH的疾病分期。
據(jù)估計(jì),美國有60%至80%的肥胖人口患有脂肪肝。目前,NASH和NAFLD還沒有得到美國聯(lián)邦藥物管理局(FDA)批準(zhǔn)的有效治療方法,因而肝臟活檢是目前疾病診斷的“金標(biāo)準(zhǔn)”,而治療該疾病的唯一方法是肝移植。診斷和治療選擇都受到嚴(yán)重的限制。
“通過人群隊(duì)列的研究使我們能夠?qū)⒋x的特征與臨床前構(gòu)建的模型進(jìn)行比較,這有助于找出其相似之處,”。
“對于識別生物標(biāo)記物,甚至是疾病的發(fā)病機(jī)制和產(chǎn)生的原因都有幫助。”
代謝組學(xué)可確定和評估NAFLD和NASH中的代謝物。代謝物在整個(gè)發(fā)展進(jìn)程上一直被用作
1)一種評估健康的方法,
2)在整個(gè)20世紀(jì)作為幫助理解組織功能的工具,
3)在當(dāng)今的臨床環(huán)境中,代謝物如葡萄糖和膽固醇,可提供對個(gè)人當(dāng)前健康狀況的及時(shí)反饋。
代謝功能失調(diào)是NASH/NAFLD的核心,而包括脂質(zhì)代謝、膽固醇代謝、炎癥反應(yīng)、氧化還原狀態(tài)和線粒體功能的評估,都能夠通過代謝物篩查實(shí)驗(yàn)來完成。
從一個(gè)生物樣本中篩選出數(shù)千種代謝物,為探究疾病機(jī)理提供了一種更全面的方法。這一方法的重要性明顯體現(xiàn)在Gilead公司應(yīng)用代謝組學(xué)建立的動物模型實(shí)驗(yàn)中。使用**輔酶A羧化酶抑制劑所取得的成功。
研究NASH的障礙
一系列不明確的風(fēng)險(xiǎn)因素與復(fù)雜的多分子途徑,都與NASH的發(fā)展進(jìn)展有關(guān)。這些風(fēng)險(xiǎn)因素包括外部輸入,如飲食、生活方式和環(huán)境因素,以及其他諸如遺傳因素、家族史和種族。所涉及的分子途徑包括脂質(zhì)代謝紊亂、氧化應(yīng)激改變、微生物代謝改變和炎癥。
其他障礙包括缺乏可靠的單從或聯(lián)合操縱基因或飲食變量而產(chǎn)生的臨床前模型。這些模型的轉(zhuǎn)化度也是個(gè)問題。
Gilead 的NASH / NAFLD動物研究模型中代謝組學(xué)的應(yīng)用
Gilead通過代謝組學(xué)為臨床前研究在NASH研究中的應(yīng)用提供了一個(gè)很好的例子。使用兩種不同的小鼠模型,Gilead已經(jīng)能夠分別研究脂肪變性和纖維化,達(dá)到了解疾病的機(jī)制以及可能的候選治療方法的目的。
在最近一次關(guān)于代謝組學(xué)的網(wǎng)絡(luò)研討會上,Gilead Sciences公司的研究科學(xué)家Jamie Bates博士說,“我們臨床前的策略是評估這兩種動物模型的機(jī)制,并通過代謝組學(xué)和轉(zhuǎn)錄學(xué)更好地理解作用機(jī)制?!?/p>
這次臨床前研究的特點(diǎn)是將快餐飲食喂養(yǎng)的小鼠模型,用肝靶向的**輔酶A羧化酶抑制劑(ACCi,是新生脂肪形成(DNL)過程中的一種必要的酶)治療5至6個(gè)月。對照組是喂正常(瘦肉)飼料的年齡匹配的小鼠。
總體研究結(jié)果表明,抑制ACCi可導(dǎo)致肝臟的脂肪變性,同時(shí)改善細(xì)胞內(nèi)線粒體功能,減輕氧化還原應(yīng)激。結(jié)果表明,快餐飲食可引起肝脂肪變性,經(jīng)ACCi治療后部分治愈。此外,膜**脂,包括**脂酰乙醇胺(PE)和**脂酰膽堿(PC),在NASH組(NAFLD和NASH患者一致)均降低,在快餐飲食模型中PEs和PC都降低,經(jīng)ACCi治療后升高。
總結(jié)
代謝組學(xué)為我們提供了比較臨床前模型試驗(yàn)和人類NASH模型的有價(jià)值的方法。雖然還需要進(jìn)行更多的研究,但未來有一天代謝組學(xué)作為較侵入性檢測更優(yōu)的評估肝纖維化的方法,揭示出了將其納入診斷工具的機(jī)會。
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