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皺紋的英文,wrinkling是什么意思,wrinkling中文翻譯,wrinkling發(fā)音、用法及例句

2025-09-03 投稿

皺紋的英文,wrinkling是什么意思,wrinkling中文翻譯,wrinkling發(fā)音、用法及例句

?wrinkling

wrinkling發(fā)音

[?r??kl??]

英:  美:

wrinkling中文意思翻譯

n. 起皺現(xiàn)象, 起皺紋

動詞wrinkle的現(xiàn)在分詞形式

wrinkling詞形變化

動詞過去分詞: wrinkled | 動詞過去式: wrinkled | 動詞第三人稱單數(shù): wrinkles | 動詞現(xiàn)在分詞: wrinkling | 形容詞: wrinkly |

wrinkling常見例句

1 、Finally, an approximate formula is presented for predicting symmetrical wrinkling critical loads.───最后,提出了一個對稱皺屈載荷的計算公式。

2 、Study on Wrinkling in Extrusion Blowing Plastic Film───擠出法吹制塑料薄膜中打褶現(xiàn)象的研究

3 、Forehead is preferred dry, however some wrinkling may occur when dog is alert.───前額是首選干的,然而當狗警惕的時候一些皺紋會出現(xiàn)。

4 、Prediction of wrinkling and crack during multi-point drawing forming process for rectangle cup with conical walls───斜壁盒形件多點拉延成形過程中起皺與拉裂預(yù)測

5 、And so he painted a picture of St matthew with a bald head and bare dusty feet awkwardly gripping the huge volume anxiously wrinkling his brow under the unaccustomed strain of writing.───于是他把圣馬太畫成這么一幅樣子:禿頂,赤著泥腳,笨拙地抓著一個大本子,由于不習(xí)慣于寫作而感到緊張,焦灼地皺起眉頭。

6 、I got to turn out and find my nigger." He looked kinder bothered, and stood there with his bills fluttering on his arm, thinking, and wrinkling up his forehead.───他那個神情仿佛有點兒為難似的,就站在那里,一邊胳膊上搭著的海報隨風(fēng)飄動,一邊在左思右想,眉頭緊皺。

7 、You are like the wind in spring, tender and warm, blowing gently into my chest and wrinkling my heart.───你是春天溫情又柔和的風(fēng),輕輕地吹到了我的懷中,把我的心吹動。

8 、Analysis method on wall wrinkling of conical parts based on reverse moulding───基于反求造型技術(shù)的錐形件側(cè)壁皺曲分析方法

9 、Keywords cage roll forming;ERW pipes;dynamic explicit algorithm;wrinkling;───排輥成形;直縫焊管;動力顯式算法;等效塑性應(yīng)變;起皺;

10 、The simulation results show that the elastic cushion and the stepped blank holder can suppress the dimpling and wrinkling defects,leading to better parts with smooth surface.───分析了拼焊板多點成形過程中出現(xiàn)的壓痕和起皺現(xiàn)象及其抑制方法,探討了焊縫偏移的影響因素。

11 、APPLICATION OF GENERALIZED CONFORMING ELEMENTS IN ELASTIC WRINKLING ANALYSIS OF THIN PLATES───廣義協(xié)調(diào)元在薄板彈性皺曲分析中的應(yīng)用

12 、3M Scotch ? 1611 Adhesive is a clean "tape-like" adhesive that adheres in seconds, yet permits material to be repositioned. It resists bleeding, staining and wrinkling plus has a smooth glue line.───1611特級萬能噴膠當需要時可隨時施用到工件上。只要手指一按,即可將適合工作要求的膠粘劑噴涂到紙張、塑料、厚紙板、泡棉、金屬和其它材料上。

13 、Ladies, make sure his wrinkles don't get wrinkles.─── 女士們 確保它的皺紋不要再長皺紋

14 、Finite element modeling has become an important tool for predicting the membrane wrinkling at present.───有限元模擬已經(jīng)成為目前薄膜褶皺預(yù)測的重要工具。

15 、Calculating formulae of wrinkling limit blankholder force in rectangular part forming with variable individual-segments blankholder force--The third research of rectangular part forming with variable individual-segments blankholder force───方盒形件分塊變壓邊力成形過程中的法蘭起皺臨界壓邊力計算--方盒形件分塊變壓邊力成形研究之三

16 、Plastic wrinkling is a typical defective mode during the THF.───塑性皺曲是管材內(nèi)高壓脹形工藝的一種典型失效形式。

17 、Keywords sheet metal;shear stress;wrinkling;experiment;numerical simulation;───板料;剪應(yīng)力;起皺;實驗;數(shù)值模擬;

18 、If you fold them while they're warm,they don't wrinkle.─── 趁床單柔暖時疊起來,就不會起皺

19 、Likewise her feminine eye took in the clothes he wore, the cheap and unaesthetic cut, the wrinkling of the coat across the shoulders, and the series of wrinkles in the sleeves that advertised bulging biceps muscles.───同樣,她那雙女性的眼睛也一眼便看透了他那身衣服,那廉價的缺乏品味的剪裁,外衣肩上的褶皺和袖子上那一連串皺紋,仿佛在為他那鼓突的二頭肌做**。

20 、Make the most of what little space you have by shoving anything you don't mind wrinkling -- socks, underwear -- into your shoes.───充分利用背包的空間,把不怕皺的物品如襪子、內(nèi)衣塞進鞋里。

21 、"Bring in--" began Melly, her brow wrinkling, and then she broke into a delighted smile.───"運進來----"媚蘭開始時皺起眉頭,但隨即露出歡快的微笑。

22 、anti wrinkling agent───抗皺劑

23 、Identification of Pathogen of Wrinkling on Sweet Osmanthus Leaf Apex───桂花葉尖皺縮病病原的鑒定

24 、Make sure that my wrinkles are all in place.─── 確保臉上的皺紋沒什么變化

25 、She took the wet gourd dipper from him, her nostrils wrinkling in distaste at the reek.───她從波克手里接過濕淋淋的長柄葫蘆勺,鼻孔立即被酒氣刺激得皺起來。

26 、The predominant failure mode in stamping of sheet metal parts are wrinkling and fracture, in general, these defects may be eliminated by appropriate manipulated the blank holder forces.───摘要起皺和斷裂是板料成形過程的主要失效模式,合理控制成形過程中壓邊力,可以消除這些缺陷,提高成形性能。

27 、Keywords stamping;deep-drawing;wrinkling;instability;formability;───沖壓;拉深;皺曲;失穩(wěn);成形性;

28 、Study on process effects of wrinkling and variable material thickness of the two-bend part───工藝對二次彎曲件起皺和料厚變化的影響研究

29 、Sorry if some of the pages are wrinkled and stuff.─── 不好意思如果有幾頁有折痕損傷什么的

30 、Keywords deep drawing;side wall wrinkling;critical BHF;───拉深成形;側(cè)壁起皺;臨界壓邊力;

31 、wrinkling of leaf face───葉面皺折

32 、Based on the analysis and evaluation of wrinkle shape, a parameter to study.the side-wall wrinkling problems in deep drawing of axisymmetrical curved parts is determind.───在分析與評價幾種表述皺紋形狀參數(shù)的基礎(chǔ)上,確定了適用于研究軸對稱曲面類零件側(cè)壁起皺問題的皺形參數(shù)。

33 、Keywords T-shaped tube;axial displacement;hydroforming;overfall pressure;wrinkling;finite element;───叉型管件;軸向位移;液壓成形;溢流壓力;起皺;有限元;

34 、His creases'll drop out but your wrinkles won't.─── 他的褶皺會消失 但你的皺紋不會

35 、Numerical Simulation of Wrinkling in Multi-point Forming for Sheet Metal without Blank Holder───板材無壓邊多點成形中起皺的數(shù)值模擬

36 、The destabilization condi tion in plastic state,the main causes of wrinkling and the pre ven tion means in the sheet drawing process of tube-shaped parts have been intro duced.───介紹了薄板拉深筒形件的塑性失穩(wěn)條件,起皺的主要原因及防止措施。

37 、The abrasiveness of the grit cloth and the increased pressure exerted on the blank simulate the draw bead effect and help reduce wrinkling in the product area (See Figure 1).───引起摩擦的粗布和增大施加在料片上的壓力來模擬拉延筋的效果從而幫助減小零件起皺(見圖一)。

38 、Keywords multi-point forming;titanium alloy;retiary metal sheet;wrinkling;numerical simulation;───多點成形;鈦合金;帶孔網(wǎng)板;起皺;數(shù)值模擬;

39 、It shows that various thermal deformations occurred as main defects in the process, such as buckling deformation, surface wrinkling and carving deformation.───變形類型有一側(cè)開口翹起變形、宏觀翹曲變形、表面起皺與局部塌陷變形等。

40 、plastic wrinkling───塑性皺曲

41 、And so he painted a picture of St matthew with a bald head and bare dusty feet, awkwardly gripping the huge volume, anxiously wrinkling his brow under the unaccustomed strain of writing.───于是他把圣馬太畫成這麼一幅樣子:禿頂,赤著泥腳,笨拙地抓著一個大本子,由于不習(xí)慣于寫作而感到緊張,焦灼地皺起眉頭。

42 、Contain Plant Herb Collagen That Can Soften Skin, Prevent Aging And Wrinkling, CureScar, So That Cells MetabolizeNormally, Your Skin May Be Elastic And Shining.───含植物草本膠原,能潤澤肌膚,防止老化及皺紋,加速傷口愈合使細胞代謝正常,讓肌膚富有彈性光澤

43 、Garment manufacturers use knitted fabrics in producing comfortable, lightweight clothing that resists wrinkling.───成衣生產(chǎn)商用針織布生產(chǎn)舒適的,能抗皺的輕薄的成衣。

44 、Certain quantity of estrogens can cause an increase in skin thickness, hydration, elasticity and a reduction in skin wrinkling.───一定量的雌激素能通過增加皮膚的厚度、水分和彈性,減少皮膚皺紋,防止皮膚老化。

45 、wall wrinkling───側(cè)壁皺曲

46 、However, in the case of deep-drawn contoured parts, wrinkling in the product area can occur from insufficient sheet material stretching.───但是,對于不規(guī)則深拉延零件,不充分的薄板材料拉伸可導(dǎo)致零件褶皺。

47 、Blank holder force(BHF) is one of the important parameters in deep drawing process of sheet metal,appropriate control of it can eliminate such defects as wrinkling and fracture.───壓邊力是板料拉延成形過程的重要工藝參數(shù)之一,合理控制壓邊力的大小,可避免成形件起皺或破裂等缺陷。

48 、Keywords curved die,drawing,wrinkling,limit drawing coefficient,numerical simulation;───曲面凹模;拉深;起皺;極限拉深系數(shù);數(shù)值模擬;

49 、The BHF can be reasonably changed with the wrinkling law by control system,so the flange formability and the part quality can be imp...───拉深過程中壓邊力通過控制系統(tǒng)可以隨拉深起皺規(guī)律而合理變化,有效地改善法蘭區(qū)變形的不均勻性,提高盒形件的成形質(zhì)量。

50 、In detail,forming rule of control and utilization of wrinkling and principle of reducing calibration pressure are desc...───最后給出了研制的典型內(nèi)高壓成形件及在汽車、航天、航空中的應(yīng)用。

51 、Analysis of Thermal Wrinkling Resulted from Non-uniform Temperature Distribution in Transpiration Cooling Formed Platelets───層板發(fā)汗冷卻結(jié)構(gòu)的非均勻溫度分布受熱皺損的求解

52 、"I can not follow you," Madeline said, wrinkling her pretty face.───“我不懂你的意思,”梅德琳皺起了漂亮臉蛋說。

53 、It is effective to replenish water, reduce wrinkling, nourish and moisture skin. Neutral and dry skin are both suitable to it.───本品系減皺美容佳品,精選多種中草藥經(jīng)高科技提煉而成,具有增加細胞組織的水份和膠原蛋白、減輕皺紋的作用。

54 、Her stockings were wrinkling at the knees.───她長襪的膝蓋處起了皺褶。

55 、According to the complaint, sunscreens protect against UVB rays, but research indicates that they do not block all UVA rays, which can cause skin cancer, aging and wrinkling.───根據(jù)指控,防曬產(chǎn)品雖可防護紫外線B射線,但研究顯示它們并不能阻擋所有的紫外線A射線,后一種射線可能造成皮膚癌、老化和皺紋。

56 、Kawai N.Critical conditions of wrinkling in deep drawing of sheet metals. JSME. 1961.───梁炳文.胡世光.板料成形塑性理論.北京:機械工業(yè)出版社,1987

57 、On the basis of constructing wrinkling model,it is calculated that the wrinkling critical tangent pressure formula in the process of drawing.───在建立皺曲模型的基礎(chǔ)上,導(dǎo)出了拉深過程中的皺曲臨界切向壓應(yīng)力的表達式.給出了不皺曲的判定式。

58 、RESEARCH ON A UNIFIED CRITERION OF INTERNAL AND EXTERNAL WRINKLING OF STRIP METAL IN-PLANE BENDING UNDER UNEQUAL COMPRESSING───板帶不均勻壓下面內(nèi)彎曲過程失穩(wěn)起皺的研究

59 、The statistic method of image analysis is used to evaluate the fabric wrinkling,analyse the texture statistics properties.───利用計算機圖像處理的統(tǒng)計分析方法對織物的抗皺恢復(fù)性能進行了系統(tǒng)地分析。

60 、Our hot drape former is used for composite work to form components avoiding fibre wrinkling (Marcelling) before being cured in an autoclave.───我們的熱成型機用于復(fù)合材料零件成型,以避免在進入熱壓罐處理前,纖維起皺(成波浪)。

61 、Keywords Multi-point forming;Die forming;Numerical simulation;Wrinkling;Tearing;Technical parameter;Material parameter;───多點成形;模具成形;數(shù)值模擬;起皺;破裂;工藝參數(shù);材料參數(shù);

62 、It also can alert users when malfunctions such as slug-pulling, wrinkling, thickness change rof raw material, mis-feeding and double-thickness etc. occur.───當故障發(fā)生(比如:褶皺、材料的厚度變化、沒有加入被沖工件、同時加入兩個被沖工件等等)的時候,系統(tǒng)可用戶報警。

63 、Keywords formability;splitting;wrinkling;instability;───成形性;破裂;起皺;失穩(wěn);

64 、Some wrinkling, with maturity, on the head extending from above the eyes to the corner of the mouth.───成熟期后,頭部可能有褶皺,從眼睛上部開始延伸至嘴角。

65 、Cigarette smoking associated with premature facial wrinkling: a clinical study and facial skin replicas analysis───吸煙對面部皺紋影響的臨床研究和圖像分析

66 、When the deformation of the workpiece exceeds permission of one step, the wrinkling defect will be produced, the multi-steps forming can resolve the problem.───當工件要求的變形程度超過一次變形的允許值時,一次成形會使工件產(chǎn)生起皺等成形缺陷,而采用多道次成形則可以解決這樣的問題。

67 、" she asked, wrinkling her pretty forehead.───她皺起美麗的額頭問道。

68 、Li Yu-ting broke off helplessly here, for Chao Po-tao suddenly gave a derisive laugh; he tilted back his head and blew a cloud of cigar smoke, his flabby face wrinkling with amusement.───李玉亭的話不得不又半途停止; 他聽得趙伯韜一聲干笑,又看見他仰臉噴一口雪茄煙,他那三角臉上浮胖胖的肌肉輕輕一下跳動。

69 、It is therefore very important to research the non-uniform deformation behaviors of the deep drawing process of tailor-welded square boxes, such as flange wrinkling and the movement of weld seams.───因此對拼焊板方盒件拉深過程中非均勻變形的研究是非常重要的,比如法蘭區(qū)起皺和焊縫的移動等。

70 、It contains collagen and leaves skin feeling smooth with elasticity, and prevent and remove neck wrinkling.───本品為勁部皮膚護理之佳品,不含激素,能收緊頸部皮膚、消除皺紋,同時還可增白、保濕,使頸部皮膚光滑、細膩。

71 、Formal wear can be packed in the last-minute to reduce wrinkling.───正式場合要穿的服裝刻意在出發(fā)前再打包以減低弄皺的機會。

72 、Also, as one ages the skin makes less natural oil and this makes the wrinkling more apparent.A moisturiser will help temporarily smooth away some early fine lines.───另外,隨著一個人年齡的增長,皮膚分泌的天然油脂會減少,而這令皺紋更加明顯。

73 、So if I want my wrinkles to go and this says that it is clinically proven to lessen wrinkles, it may not be something I can even see at home.─── 所以如果我想要去皺 而這上面說 臨床證明它可以減少皺紋 但可能我在家也看不到效果

74 、Aftertreatment increases weight to puts in order , puts softly in order and able to bear wrinkling putting.───后整理有增重整理、柔軟整理和防縮耐皺整理。

75 、The daffodils which challenge so proudly and splendidly the boisterous March winds are soon shrivelled and defeated, limply wrinkling to remind us of the inevitable ravages of time.───大自然催促生命之花怒放,催促得青春煥發(fā)出激昂奔放之美,但這是一種驟然迸發(fā)的感官美,它迫不及待地急變?yōu)橄募镜臐馄G繁華。

76 、Whatever aging, decrepitude, brokenness, graying, wrinkling, decline of life-force, weakening of the faculties of the various beings in this or that group of beings, that is called aging.───于各種眾生之部類,各種眾生之歿、滅、破壞、死、破滅、諸蘊之破壞,遺骸之放棄,此謂之死。

77 、You've been wrinkled and disheveled for two days.─── 你這樣衣衫不整 頭發(fā)蓬亂已經(jīng)兩天了

78 、Keywords numerical simulation;drawbead;wrinkling;inadequate stretch areas;───數(shù)值模擬;壓料筋;起皺;未充分拉深;

79 、Keywords plastic buckling;deep drawability;energy method;blankholder force;wrinkling;───塑性屈曲;深沖性能;能量法;壓邊力;起皺;

80 、Keywords ZE10 magnesium alloy;deep drawing;limited drawing ratio;wrinkling;drawability;───ZE10鎂合金;熱拉深;極限拉深比;起皺;拉深性能;

81 、It appears we still have a few wrinkles to iron out.─── 看來我們還是有些東西要先擺平

82 、I didn't want it to wrinkle, so I brought it in.─── 我不想讓它皺了 所以我就拿來了

83 、Low elasticity, imparting a hard, smooth texture, makes linen subject to wrinkling.───彈性較低,使得質(zhì)地堅硬光滑,亞麻制品容易起皺紋。

84 、Removal of packet wrapping film wrinkling in the Focke 350 cigarette packer───350包裝機組小包透明紙起皺現(xiàn)象的消除

85 、When bound conditions are known, it can simulate metal flowing and wrinkling process of the noncontact region in sheet metal forming.───在給定邊界條件的情況下,該軟件能模擬板料沖壓成 形過程中懸空區(qū)起皺過程,能比較準確地預(yù)測懸空區(qū)金屬的流動狀況 。

86 、Study on Wrinkling on Surface of Nature Latex Dipped Products───天然膠乳浸漬制品表面起皺的研究

87 、Treat Wrinkling for Stitching Side Wall of Radial Tire───子午胎胎側(cè)壓合打褶問題的解決

88 、side wall wrinkling───側(cè)壁起皺

89 、Just as there are foods that enhance skin health such as fresh fruits and vegetables there are ones that can harm skin and increase the risk of skin laxity and wrinkling.───就像一些食物可以增強皮膚健康,如新鮮的水果和蔬菜,相對的也會存在一些食物,可以傷害和增加肌膚老化,讓皮膚松弛和產(chǎn)生皺紋。

twinkling是什么意思?

twinkling英 [?tw??kl??] 美 [?tw??kl??]

n.閃爍; 眨眼間; 詼諧的閃光; 一剎那;

adj.閃爍的,閃亮的,閃耀的;

v.閃爍( twinkle的現(xiàn)在分詞 ) (眼睛) 閃亮; (經(jīng)光照耀而) 閃閃發(fā)光; (舞蹈者的雙腳) 輕快地移動;

[網(wǎng)絡(luò)]熒熒的; 閃爍的; 瞬間;

[例句]The only motion seemed to be in the glowing, twinkling stars, every bladeof grass was asleep.似乎只有那些閃爍發(fā)光的星星在移動,每一片草都熟睡了。[其他]形近詞: ankling crinkling wrinkling

合理選擇煙酰胺產(chǎn)品

含煙酰胺成分的產(chǎn)品很多,在選擇的時候一看濃度,二看配方和成分搭配。

➠濃度

煙酰胺濃度的選擇是一個很微妙的判斷, 濃度既不能太高,也不能太低 。一方面足夠的濃度才能保證效果,已經(jīng)有大量的實驗研究證實, 在一定的范圍內(nèi) 煙酰胺 抑制色素的效果隨濃度增加而增強 1;但是另一方面,也要考慮到太高濃度的煙酰胺對皮膚可能造成刺激。

煙酰胺最合適的濃度是多少呢?就我個人掌握的信息來說, 目前沒有看到有文獻歸納出最佳的濃度,也沒有文獻系統(tǒng)地比較不同濃度煙酰胺的效果和刺激 ,只有一些單獨的報道。例如保濕/修復(fù)屏障結(jié)構(gòu)2-3和治療特應(yīng)性皮炎方面4有報道用2%的濃度,淡化色素5-6和治療光老化7-9有報道用5%的濃度。

能夠確定的是, 主流的、正規(guī)的研究文章基本都是以5%作為上限濃度 。為什么選擇這個上限?不知道,我估計可能是基于臨床經(jīng)驗的總結(jié),高于這個濃度的效果提升不多,但是刺激性會上升。

綜合考慮以上研究的結(jié)果,我個人認為 確定自己對煙酰胺耐受的話,煙酰胺的濃度越高越好,排名越前越好 。 用在美白、改善膚色方面 4% 會穩(wěn)妥一些,5%是上限 。至于下限就不好說,因為廠家不可能自曝其短。大致來說,如果煙酰胺的排名在成分表的十名開外,這個濃度就算是比較低了,效果比較難保證,不值得購買。 假如不確定自己對煙酰胺是否耐受,就從低濃度開始用起 。

➠搭配

雖然煙酰胺有多種效果,但 無論在哪個領(lǐng)域,它都不是效果最好的,它扮演的角色其實是輔助其他成分更好地發(fā)揮作用 。當煙酰胺用于美白、改善色素沉著的時候,就更需要和其他成分一起協(xié)同發(fā)揮作用。從作用機理來說,改善色素沉著的藥/藥妝成分主要有三條作用途徑10:

1.減少黑素的合成,例如氫醌、熊果苷、曲酸。

2.干擾黑素小體轉(zhuǎn)運,例如煙酰胺、大豆蛋白。

3.加快角質(zhì)細胞代謝,例如果酸、水楊酸、維A酸。

煙酰胺能干擾黑素小體輸送到角質(zhì)層,但它不能減少黑素的合成;此外,它還有兩個特點讓人很不滿意5-6:第一,用了4-8周以后效果就會進入一個瓶頸期,再用下去也沒有明顯改善;第二,效果是可逆的,用了38周之后發(fā)現(xiàn)膚色回到原樣。 所以單獨用煙酰胺來美白的效果不盡如人意,和黑素抑制劑(如熊果苷/氫醌)協(xié)同使用的時候,效果才會更好 。

煙酰胺的搭配還有一個技術(shù)細節(jié)很少會有人注意到,那就是它和尼泊金酯類防腐劑能夠形成配合物。煙酰胺易溶于水,而尼泊金酯類防腐劑難溶于水, 兩者共同使用的時候能夠形成配合物,促進尼泊金酯在水相中的溶解 11。這樣做有兩個好處,一是保證防腐劑在水相中有足夠的濃度,抑制細菌滋生;二是減少防腐劑的透皮吸收,降低對皮膚刺激。所以在設(shè)計配方的時候,可以優(yōu)先考慮采用尼泊金酯的防腐體系。

➠品牌美譽度

煙酰胺是最后一個產(chǎn)能轉(zhuǎn)移到中國的維生素品種,市場競爭較為激烈,市場集中度較低,眾多本土企業(yè)和國外企業(yè)(尤其是龍沙和帝斯曼)正在通過激烈的競爭,來進行產(chǎn)業(yè)分布的調(diào)整。不同廠家生產(chǎn)的煙酰胺,純度肯定不一樣。 品牌美譽度高的大的公司或者代工廠家能夠拿到純度較高的優(yōu)質(zhì)原料,降低雜質(zhì)的刺激 。不過原料的水很深,一般的消費者未必能夠了解里面的門道。

➠產(chǎn)品簡析

很多產(chǎn)品都有添加煙酰胺,這里只挑幾個物美價廉的品牌作為代表來進行分析。

1.OLAY新生塑顏奇跡賦能肌底液

寶潔的技術(shù)底蘊沒的說,玩煙酰胺不是一般的6,從SK-II到OLAY都有它的身影。之所以把這個拿出來,是因為產(chǎn)品里面沒有什么多余的成分,不像新生塑顏金純面霜或者多效修護霜那樣,為了達到即時可見的效果而加入二氧化鈦、云母或者色素等物質(zhì)。如果想試一試煙酰胺的效果,可以考慮這個產(chǎn)品。

煙酰胺具體濃度不詳,但是從成分表來看,排名僅次于水,位居第二位,濃度應(yīng)該有保障;搭配多肽+3種植物提取物+維生素E+維生素C,兼顧了美白抗氧化修復(fù)等等功能,是一個十全大補的配方,適合熟齡肌膚用。有人認為配方里面的肌醇能夠起到美白/淡化色斑作用,對此我持保留意見,肌醇更多的還是起保濕作用,對炎癥后色素沉著沒有(直接的)抑制作用12。

官方介紹:http://www.olay.com.cn/skin-care-products/olay_regenerist_miracle_boost_youth_pre-essence-40ml

2.貝德瑪賦妍煙酰胺保濕滋潤修護霜(ATODERM PP BAUME)

這個產(chǎn)品是用高濃度的礦物油和合成酯(聚二甲基硅氧烷)來滋潤皮膚,用煙酰胺促進神經(jīng)酰胺和膽甾醇的合成,修復(fù)皮膚屏障,整體配方樸實無華,適合干性皮膚。

官方介紹:

https://detail.tmall.com/item.htm?spm=a1z10.5-b.w4011-2674845487.49.HI5tWc&id=16916780136&rn=c0e16a649cc692e936b26800a142c7e2&abbucket=5&skuId=49168940756

3. CeraVeR面部夜間補水保濕乳液(Facial Moisturizing Lotion PM)

煙酰胺能增加皮膚屏障結(jié)構(gòu)中的細胞間脂質(zhì)(特別是神經(jīng)酰胺)的合成,改善屏障功能。所以這個產(chǎn)品的設(shè)計思路是用神經(jīng)酰胺+膽甾醇+脂肪酸修復(fù)角質(zhì)屏障結(jié)構(gòu),用煙酰胺促進神經(jīng)酰胺和膽甾醇的合成。

官方介紹:

http://www.cerave.com/our-products-moisturizers-pm-facial-moisturizing-lotion

關(guān)于貝德瑪和CeraVe的這類產(chǎn)品,我一直有一個疑問:什么樣的膚質(zhì)才需要重建屏障結(jié)構(gòu)、補充細胞間脂質(zhì)呢?毫無疑問應(yīng)該是偏敏感的膚質(zhì)。敏感性皮膚用煙酰胺,這樣會不會引起皮膚的刺激呢?截止到本文寫作日期為止(2017年6月23日),在CeraVe天貓官方旗艦店上并沒有這款產(chǎn)品出售的信息,客服給出的解釋是該款產(chǎn)品已經(jīng)售完,短期內(nèi)沒有上架的通知,可見我的疑問并不是沒有根據(jù)的。 敏感性皮膚如果不確定對煙酰胺是否耐受的話,最好還是不要冒這個險,用神經(jīng)酰胺、膽甾醇這些成分來修復(fù)角質(zhì)屏障就好了 。

4.肌美鑰妝明膚凝膠

這是我開發(fā)的產(chǎn)品,以煙酰胺(4%)+α-熊果苷(2%)作為核心美白成分,一頭一尾分別搭配具有活血化瘀作用的玫瑰花水和具有美白作用的維生素C。這個組合兼顧了淡化黑色素通路中的三條途徑,濃度也是經(jīng)過慎重的考慮,力求在保證安全性的前提下,盡可能地增強效果。

保濕用的是經(jīng)典的甘油和透明質(zhì)酸鈉,有些人覺得會覺得有一點點粘膩,如果是后續(xù)要用防曬霜或者隔離霜之類的含粉產(chǎn)品,還可能出現(xiàn)搓泥的現(xiàn)象,這是由凝膠的質(zhì)地所決定的。所以后續(xù)使用的時候盡量避免用含粉產(chǎn)品,或者把它放到晚上用。防腐劑使用水溶性的苯氧乙醇和油溶性的羥苯甲酯,保證水相和油相中的都能夠有效抑制細菌。

官方介紹:

https://weidian.com/item.html?itemID=1880074921

參考文獻

1. Greatens A, Hakozaki T, Koshoffer A et al. Effective inhibition ofmelanosome transfer to keratinocytes by lectins and niacinamide is reversible.Exp Dermatol 2005;14(7):498–508.

2. Tanno O, Ota Y, Kitamura N, Katsube T, Inoue S. Nicotinamide increasesbiosynthesis of ceramides as well as other stratum corneum lipids to improvethe epidermal permeability barrier. Br J Dermatol 2000;143(3):524–531.

3. Draelos ZD, Ertel K, Berge C, Amburgey M. Niacinamide-containing facialmoisturizer improves skin barrier and benefts subjects with rosacea. CUTIS–NewYork 2005;76(2):135.

4. Soma Y, Kashima M, Imaizumi A, et al. Moisturizing effects of topicalnicotinamide on atopic dry skin. Int J Dermatol, 2005, 44:197-202.

5. Greatens A, Hakozaki T, Koshoffer A et al. Effective inhibition ofmelanosome transfer to keratinocytes by lectins and niacinamide is reversible.Exp Dermatol 2005;14(7):498–508.

6. Hakozaki T, Minwalla L, Zhuang J, et al. The effect of niacinamide onreducing cutaneous pigmentation and suppression of melanosome transfer. Br JDermatol, 2002, 147: 20-31.

7. Bissett DL, Miyamoto K, Sun P, Li J, Berge CA. Topical niacinamidereduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots inaging facial skin. Int J Cosmet Sci 2004;26(5):231–238

8. Bissett DL, Oblong JE, Berge CA. Niacinamide: A B vitamin that improvesaging facial skin appearance. Dermatol Surg, 2005, 31(7Pt 2): 860-865.

9. Damian DL, Clare RS, Michael S, et al. UV radiation-induced immunosuppressionis greater in men and prevented by topical nicotinamide. J Invest Dermatol, 2008,128(2):447-454.

10. Cosmeceuticals and active cosmetics,Third Edition.

11. Sara N. Franca Z. Stefania B. et al. Association of nicotinamide withparabens Effect on solubility, partition and transdermal permeation. European JPharmaceutics and Biopharmaceutics, 2008,69(2):613-621

12.煙酰胺對Toll樣受體介導(dǎo)的炎癥后色素沉著的研究_陳琴怡

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